DENARASE is a highly active endonuclease from Serratia marcescens. This enzyme is widely used in biopharmaceutical manufacturing to quantitatively eliminate host cell DNA and RNA during the production of biologicals and vaccines, as well as for viscosity reduction in biotechnology applications. 

DENARASE has a high purity of ≥ 99 % and is manufactured in full compliance with GMP requirements, without the use of antibiotics and only with raw materials of non-animal origin. 

The patent-protected production process is based on the recombinant expression in a Bacillus sp., combining high product yields with the advantages of an endotoxin-free production strain. DENARASE meets all relevant safety and quality requirements for the use in regulated fields. 

Please use the inquiry form below or contact us via to find out what c-LEcta‘s DENARASE can do for your bioprocess demands or to request your individual quotation.

DENARASE is a proprietary product of c-LEcta GmbH, Germany. For more information about the company please visit our corporate website:

Activity: >250 U/μl
Purity: ≥ 99%
Production host: Bacillus sp.

Full compliance with GMP
Manufacturing free of products of animal origin
Endotoxin-free production strain

Form: buffered aqueous glycerol solution
Storage Temperature: -20°C


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